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Rafael Roesler Selected Research

Gastrin-Releasing Peptide

5/2017A Placebo-Controlled Crossover Trial of Gastrin-Releasing Peptide in Childhood Autism.
9/2016Improvement in Symptoms of Autism Spectrum Disorder in Children With the Use of Gastrin-Releasing Peptide: An Open Trial.
5/2016Improvement of autism spectrum disorder symptoms in three children by using gastrin-releasing peptide.
10/2012Gastrin-releasing peptide receptor antagonism induces protection from lethal sepsis: involvement of toll-like receptor 4 signaling.
1/2012The gastrin-releasing peptide receptor as a marker of dysplastic alterations in cervical epithelial cells.
9/2010Protective effect of gastrin-releasing peptide receptor antagonist in carrageenan-induced pleural inflammation in rats.
8/2010Effects of the gastrin-releasing peptide antagonist RC-3095 in a rat model of ulcerative colitis.
11/2009Effects of an antagonist of the gastrin-releasing peptide receptor in an animal model of uveitis.
8/2009A gastrin-releasing peptide receptor antagonist stimulates Neuro2a neuroblastoma cell growth: prevention by a histone deacetylase inhibitor.
6/2009Anti-proliferative effect of the gastrin-release peptide receptor antagonist RC-3095 plus temozolomide in experimental glioblastoma models.
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Rafael Roesler Research Topics

Disease

52Neoplasms (Cancer)
12/2022 - 07/2003
13Medulloblastoma
12/2022 - 12/2009
13Brain Neoplasms (Brain Tumor)
06/2022 - 01/2008
11Glioma (Gliomas)
01/2017 - 05/2008
10Sepsis (Septicemia)
04/2017 - 01/2006
9Glioblastoma (Glioblastoma Multiforme)
09/2020 - 01/2008
5Autistic Disorder (Autism)
05/2017 - 03/2007
4Inflammation (Inflammations)
12/2021 - 05/2010
4Neuroblastoma
10/2021 - 06/2009
4Ewing Sarcoma (Sarcoma, Ewing)
09/2018 - 02/2014
4Cognitive Dysfunction
11/2017 - 12/2009
4Colorectal Neoplasms (Colorectal Cancer)
03/2017 - 01/2007
3Lymphoma (Lymphomas)
03/2021 - 06/2010
3Squamous Cell Carcinoma of Head and Neck
11/2019 - 02/2014
3Breast Neoplasms (Breast Cancer)
11/2017 - 12/2009
3Autism Spectrum Disorder
05/2017 - 05/2016
3Colonic Neoplasms (Colon Cancer)
11/2013 - 01/2009
3Gastritis
06/2013 - 08/2009
3Mental Disorders (Mental Disorder)
07/2007 - 12/2006
2Urinary Bladder Neoplasms (Bladder Cancer)
08/2022 - 03/2018
2Adenocarcinoma
11/2020 - 01/2010
2Leukemia
09/2016 - 06/2010
2Memory Disorders (Memory Loss)
01/2016 - 10/2011
2Lung Neoplasms (Lung Cancer)
01/2016 - 01/2014
2Neurodevelopmental Disorders
01/2016 - 03/2007
2Head and Neck Neoplasms (Head and Neck Cancer)
02/2014 - 10/2013
2Arthritis (Polyarthritis)
06/2013 - 01/2012
2Uveitis
06/2013 - 11/2009
2Mania (Manias)
06/2012 - 03/2010
2Carcinoma (Carcinomatosis)
01/2012 - 01/2009
2Body Weight (Weight, Body)
01/2011 - 06/2010
2Ulcerative Colitis
08/2010 - 03/2010
2Bipolar Disorder (Manic Depressive Psychosis)
07/2007 - 12/2006
2Central Nervous System Diseases (CNS Diseases)
06/2007 - 03/2007

Drug/Important Bio-Agent (IBA)

31Bombesin Receptors (Bombesin Receptor)IBA
01/2017 - 05/2004
16Brain-Derived Neurotrophic Factor (BDNF)IBA
11/2020 - 01/2010
16Gastrin-Releasing PeptideIBA
05/2017 - 02/2004
14Tpi(6)-Leu(13)-psi(CH2NH)-Leu(14)- bombesin (6-14)IBA
06/2013 - 01/2006
10Nerve Growth Factors (Neurotrophins)IBA
09/2020 - 01/2009
10Histone Deacetylase InhibitorsIBA
03/2020 - 08/2009
9Phosphotransferases (Kinase)IBA
10/2021 - 01/2013
7Biomarkers (Surrogate Marker)IBA
12/2022 - 06/2009
7BombesinIBA
11/2007 - 07/2003
6EnzymesIBA
12/2022 - 01/2009
6DNA (Deoxyribonucleic Acid)IBA
12/2022 - 06/2009
6TropomyosinIBA
09/2020 - 01/2013
6ErbB Receptors (EGF Receptor)IBA
05/2019 - 01/2007
5Histones (Histone)IBA
12/2022 - 01/2016
5Pharmaceutical PreparationsIBA
06/2022 - 06/2009
5NeuropeptidesIBA
01/2013 - 05/2004
5Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2012 - 06/2007
4ChromatinIBA
12/2022 - 12/2013
4Nerve Growth Factor (NGF)IBA
01/2019 - 01/2009
4trkB ReceptorIBA
01/2019 - 01/2010
4Proteins (Proteins, Gene)FDA Link
03/2018 - 12/2003
4Dextroamphetamine (Dexedrine)FDA LinkGeneric
06/2012 - 07/2007
4Peptides (Polypeptides)IBA
06/2007 - 07/2003
3tyrosine receptor (receptor, tyrosine)IBA
10/2021 - 01/2017
3Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
11/2019 - 03/2018
3Messenger RNA (mRNA)IBA
05/2019 - 05/2008
3LigandsIBA
04/2017 - 03/2010
3Butyric Acid (Butanoic Acid)IBA
02/2014 - 06/2011
3CytokinesIBA
10/2012 - 01/2006
3ParaffinIBA
04/2010 - 01/2007
3AntioxidantsIBA
08/2009 - 12/2003
3ApomorphineFDA Link
12/2006 - 05/2002
2Transcription Factors (Transcription Factor)IBA
06/2022 - 04/2021
2MicroRNAs (MicroRNA)IBA
11/2021 - 10/2016
2Antineoplastic Agents (Antineoplastics)IBA
10/2021 - 06/2011
2Sirolimus (Rapamycin)FDA Link
01/2021 - 01/2012
2Purinergic P1 Receptors (Adenosine Receptor)IBA
12/2020 - 01/2015
2Nerve Growth Factor Receptors (Neurotrophin Receptors)IBA
09/2020 - 01/2013
2Mitogen-Activated Protein KinasesIBA
06/2020 - 01/2014
2Histone Deacetylases (Histone Deacetylase)IBA
05/2019 - 09/2018
25'-Nucleotidase (5' Nucleotidase)IBA
03/2018 - 01/2015
2Therapeutic UsesIBA
05/2016 - 05/2010
2Adenosine (Adenocard)FDA LinkGeneric
01/2015 - 01/2012
2A-Form DNA (A-DNA)IBA
11/2012 - 06/2009
2Adenosine Triphosphate (ATP)IBA
01/2012 - 03/2011
2Acetylcysteine (Siran)FDA LinkGeneric
03/2011 - 04/2010
2Indomethacin (Indometacin)FDA LinkGeneric
03/2011 - 08/2009
2Omeprazole (Prilosec)FDA LinkGeneric
03/2011 - 08/2009
2mangiferinIBA
01/2011 - 06/2010
2Glutamate Receptors (Glutamate Receptor)IBA
11/2010 - 02/2010
2KIR ReceptorsIBA
08/2010 - 03/2010
2Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
08/2010 - 06/2010
2HLA Antigens (Human Leukocyte Antigens)IBA
08/2010 - 03/2010
2Type 4 Cyclic Nucleotide PhosphodiesterasesIBA
03/2010 - 05/2009
2N-Methylaspartate (NMDA)IBA
02/2010 - 04/2004
2N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA
02/2010 - 11/2008
2Dizocilpine Maleate (Dizocilpine)IBA
02/2010 - 04/2004
2Superoxide DismutaseIBA
06/2009 - 12/2003
2Phosphatidylinositols (Phosphatidylinositol)IBA
06/2009 - 05/2008
2Antipsychotic Agents (Antipsychotics)IBA
08/2007 - 07/2007

Therapy/Procedure

17Therapeutics
11/2020 - 05/2002
8Drug Therapy (Chemotherapy)
06/2022 - 08/2006
5Radiotherapy
08/2022 - 06/2009
3Ligation
04/2010 - 01/2006
2Aftercare (After-Treatment)
01/2021 - 12/2003
2Intraperitoneal Injections
01/2011 - 06/2010